Course Topics

Introduction to Reaction Kinetics

Reaction Kinetics: The study of rates of chemical reactions, factors affecting rates, and reaction mechanisms.

Chemical Reactions Classification by Rate:

Type Examples Characteristics
Very Fast Reactions Ionic reactions, neutralization Completed in microseconds
Very Slow Reactions Rusting of iron, weathering Take years to complete
Moderately Slow Reactions Esterification, hydrolysis Take minutes to hours
Memory Tip

Kinetics = Rates + Mechanisms + Factors – Remember the three pillars of reaction kinetics!

Rate of Reaction

Definition: The change in concentration of a reactant or product per unit time.

Rate = -Δ[Reactant]/Δt = +Δ[Product]/Δt

Units: mol dm⁻³ s⁻¹ (moles per cubic decimeter per second)

A
B
C
CRITICAL CONCEPT: Rate of reaction is NOT constant throughout the reaction. It decreases as reactants are consumed. Initial rate is the fastest rate.
Memory Tip

Rate = Concentration change ÷ Time taken. Units always have “per second” (s⁻¹) or similar time unit!

Rate Constant (k)

Definition: The proportionality constant in the rate equation. Rate = k[Reactants]ⁿ

Key Properties:

  • Constant at constant temperature
  • Independent of concentration
  • Depends on temperature (increases with temperature)
  • Characteristic of a specific reaction

Rate of Reaction

  • Changes with time
  • Depends on concentration
  • Units: mol dm⁻³ s⁻¹
  • Measured experimentally

Rate Constant (k)

  • Constant at constant T
  • Independent of concentration
  • Units vary with order
  • Characteristic of reaction
Memory Tip

k is like the “personality” of a reaction – unique, constant at same T, and tells how fast it inherently is!

Factors Affecting Reaction Rate

Factor Effect on Rate Reason
Nature of Reactant Ionic reactions faster than covalent Ions react immediately on contact
Concentration Rate ∝ Concentrationⁿ More particles = more collisions
Surface Area Rate increases with surface area More exposed particles for reaction
Temperature Rate doubles for every 10°C rise More particles have E ≥ Eₐ
Catalyst Increases rate without being consumed Lowers activation energy
Light Increases photochemical reactions Provides energy for activation
Memory Tip

Remember: Concentration, Temperature, Catalyst, Surface area, Nature = CTCSN!

Arrhenius Equation

Equation: k = A e^(-Eₐ/RT)

k = A e^(-Eₐ/RT)

Where:

  • k = rate constant
  • A = frequency factor (collision frequency)
  • Eₐ = activation energy (J/mol)
  • R = gas constant (8.314 J/mol·K)
  • T = temperature (K)
CRITICAL CONCEPT: The Arrhenius equation quantitatively explains the effect of temperature on reaction rate. Higher temperature means more molecules have energy ≥ Eₐ, so rate increases exponentially.

Logarithmic Form: ln k = ln A – Eₐ/RT

Memory Tip

Arrhenius Equation: k = A e^(-Eₐ/RT) – Think “k equals A times e to the negative Ea over RT”!

Half-Life and Order of Reaction

Half-Life (t₁/₂): Time required for concentration to reduce to half its initial value.

Order Half-Life Relation Dependence on [A]₀
Zero t₁/₂ = [A]₀/2k Directly proportional
First t₁/₂ = 0.693/k Independent
Second t₁/₂ = 1/(k[A]₀) Inversely proportional
Third t₁/₂ = 3/(2k[A]₀²) Inversely proportional to square
Memory Tip

First order: Constant half-life! Zero order: t₁/₂ increases as [A]₀ increases. Second order: t₁/₂ decreases as [A]₀ increases!

Order of Reaction

Definition: Sum of exponents in the rate equation.

Rate = k[A]^m[B]^n → Order = m + n

Types of Reactions:

Order Rate Equation Example
Zero Rate = k Photochemical reactions
First Rate = k[A] Radioactive decay, N₂O₅ decomposition
Second Rate = k[A]² or k[A][B] 2HI → H₂ + I₂
Third Rate = k[A]³ or k[A]²[B] 2NO + Cl₂ → 2NOCl
Pseudo First Rate = k[A][B] but [B] is constant Ester hydrolysis in excess water
CRITICAL CONCEPT: Order is an EXPERIMENTAL quantity. It cannot be determined from the balanced chemical equation alone. It may be zero, fractional, or negative.
Memory Tip

Order = Sum of exponents in rate law. NOT from stoichiometry! Always determine experimentally!

Determination of Order

Methods to Determine Order:

  1. Initial Rate Method: Measure initial rates at different concentrations
  2. Half-Life Method: Study how t₁/₂ changes with [A]₀
  3. Integrated Rate Law Method: Plot appropriate graphs
  4. Differential Method: Use rate vs concentration data
Order Integrated Rate Law Linear Plot
Zero [A] = [A]₀ – kt [A] vs t (straight line, slope = -k)
First ln[A] = ln[A]₀ – kt ln[A] vs t (straight line, slope = -k)
Second 1/[A] = 1/[A]₀ + kt 1/[A] vs t (straight line, slope = k)
Memory Tip

Zero order: [A] vs t linear. First order: ln[A] vs t linear. Second order: 1/[A] vs t linear!

Activation Energy & Activated Complex

Activation Energy (Eₐ): Minimum energy required for effective collisions.

Activated Complex: High-energy transitional state between reactants and products.

CRITICAL CONCEPT:
  • Exothermic: Eₐ(forward) < Eₐ(reverse)
  • Endothermic: Eₐ(forward) > Eₐ(reverse)
  • ΔH = Eₐ(forward) – Eₐ(reverse)

Key Points:

  • Catalysts lower Eₐ
  • Higher Eₐ means slower reaction
  • Activated complex has partial bonds
  • Cannot be isolated
Memory Tip

Activation energy is the “energy hill” molecules must climb to react. Catalysts make this hill smaller!

Enzyme Catalysis

Enzymes: Biological catalysts (proteins) that speed up biochemical reactions.

Mechanism: Enzyme-Substrate Complex → Products + Enzyme

Enzyme Reaction Catalyzed Substrate
Urease Urea hydrolysis Urea
Invertase Sucrose hydrolysis Sucrose
Zymase Glucose fermentation Glucose
Diastase Starch hydrolysis Starch
Maltase Maltose hydrolysis Maltose
CRITICAL CONCEPT: Enzymes are highly specific due to their active sites. They follow Michaelis-Menten kinetics and show maximum velocity (Vmax) and Michaelis constant (Km).
Memory Tip

Enzyme names usually end in “-ase”! They’re like specialized tools – each enzyme fits only its specific substrate!

Units of Rate Constant

General Formula: Units of k = (concentration)¹⁻ⁿ (time)⁻¹

Order (n) Units of k Example
0 mol dm⁻³ s⁻¹ Same as rate
1 s⁻¹ Radioactive decay
2 dm³ mol⁻¹ s⁻¹ 2HI → H₂ + I₂
3 dm⁶ mol⁻² s⁻¹ 2NO + Cl₂ → 2NOCl
k units = (mol dm⁻³)¹⁻ⁿ s⁻¹
Memory Tip

Units of k: As order increases, power of concentration becomes more negative. 1st order: s⁻¹ (simplest)!

Reaction Mechanisms

Rate Determining Step (RDS): Slowest step in a multi-step reaction mechanism.

Reaction Intermediate: Species formed in one step and consumed in another, not in overall equation.

EXAMPLE: NO₂ + CO → NO + CO₂

Rate = k[NO₂]² (independent of [CO])

Mechanism:

  1. NO₂ + NO₂ → NO₃ + NO (slow, RDS)
  2. NO₃ + CO → NO₂ + CO₂ (fast)

NO₃ is reaction intermediate

Memory Tip

Rate law comes from RDS! Intermediates don’t appear in overall equation but appear in mechanism!