Posology in Pharmacology MCQs with answers

Master Posology in Pharmacology with MCQs covering drug dosage, calculations, and administration principles. Strengthen your understanding of key concepts for successful exam preparation.

Posology MCQs

  1. Posology is the study of:
  • A) Drug interactions
  • B) Dosage and administration of drugs
  • C) Drug side effects
  • D) Drug formulations
  • Answer: B
  1. What is the primary aim of posology?
  • A) To reduce drug costs
  • B) To maximize therapeutic effects and minimize toxicity
  • C) To enhance drug stability
  • D) To improve patient compliance
  • Answer: B
  1. The term “therapeutic window” refers to:
  • A) The range of doses that provides therapeutic effects without toxicity
  • B) The time frame for drug absorption
  • C) The time a drug remains in the body
  • D) The duration of treatment
  • Answer: A
  1. What does the term “loading dose” refer to?
  • A) The dose given after the initial dose
  • B) A higher dose administered to rapidly achieve therapeutic levels
  • C) A reduced dose for patients with renal impairment
  • D) The standard dose for maintenance therapy
  • Answer: B
  1. Which factor does NOT influence the dosage of a drug?
  • A) Age
  • B) Gender
  • C) Time of day
  • D) Weight
  • Answer: C
  1. In pediatrics, dosing is often calculated based on:
  • A) Adult dosing guidelines
  • B) Body surface area (BSA)
  • C) Time of day
  • D) Weight only
  • Answer: B
  1. The term “maintenance dose” refers to:
  • A) The initial dose given at the start of treatment
  • B) A dose given to maintain therapeutic drug levels
  • C) A higher dose to quickly achieve effects
  • D) A reduced dose for elderly patients
  • Answer: B
  1. What is the main reason for calculating dosage adjustments in elderly patients?
  • A) Increased metabolism
  • B) Decreased liver and kidney function
  • C) Decreased body weight
  • D) Increased drug absorption
  • Answer: B
  1. Which term describes the amount of drug administered over a specific period?
  • A) Dosage
  • B) Dose
  • C) Frequency
  • D) Concentration
  • Answer: A
  1. What is the recommended practice for converting dosages between different routes of administration?
    • A) Use the same dosage for all routes
    • B) Apply a conversion factor based on bioavailability
    • C) Only use oral doses for all routes
    • D) Administer the same volume regardless of the route
    • Answer: B
  2. When calculating drug doses for animals, which is a common reference used?
    • A) Body weight
    • B) Age only
    • C) Diet type
    • D) Breed only
    • Answer: A
  3. In pharmacology, “unit dose” refers to:
    • A) The total amount of a drug in a prescription
    • B) The specific amount of medication given at one time
    • C) The amount of drug in a vial
    • D) A dosage form intended for prolonged release
    • Answer: B
  4. The term “therapeutic index” refers to:
    • A) The ratio of toxic dose to therapeutic dose
    • B) The concentration of drug in the blood
    • C) The absorption rate of the drug
    • D) The time taken for drug clearance
    • Answer: A
  5. Which type of dosing regimen provides a constant plasma level of a drug?
    • A) Intermittent dosing
    • B) Continuous infusion
    • C) Single dose
    • D) Short-term treatment
    • Answer: B
  6. What does “titration” in pharmacology refer to?
    • A) Determining the correct dosage through gradual adjustment
    • B) Measuring blood pressure during treatment
    • C) Evaluating patient compliance
    • D) The process of excretion
    • Answer: A
  7. Which of the following would typically require a dosage adjustment?
    • A) Age
    • B) Weight
    • C) Organ function
    • D) All of the above
    • Answer: D
  8. A drug with a narrow therapeutic index requires:
    • A) Close monitoring of blood levels
    • B) Larger doses
    • C) Infrequent administration
    • D) Reduced bioavailability
    • Answer: A
  9. Which of the following is NOT a common route of drug administration?
    • A) Intravenous
    • B) Sublingual
    • C) Intraocular
    • D) Intramuscular
    • Answer: C
  10. What is the primary consideration when determining dosages for pregnant patients?
    • A) The weight of the fetus
    • B) Potential drug transfer to the fetus
    • C) Maternal comfort
    • D) The duration of pregnancy
    • Answer: B
  11. In which situation might a healthcare provider choose to administer a drug by the parenteral route?
    • A) When oral absorption is preferred
    • B) When rapid onset of action is required
    • C) When the patient can swallow pills
    • D) When a drug is not soluble
    • Answer: B
  12. What is the significance of the “dosage form” in pharmacology?
    • A) It affects how the drug is marketed
    • B) It determines the route of administration and release characteristics
    • C) It has no impact on efficacy
    • D) It only relates to the size of the drug
    • Answer: B
  13. Drugs with high protein binding may:
    • A) Be more readily eliminated
    • B) Have reduced free drug concentrations
    • C) Require higher doses for efficacy
    • D) All of the above
    • Answer: D
  14. What does “dose-response relationship” describe?
    • A) The relationship between drug formulation and its marketing
    • B) The correlation between drug dosage and the extent of the therapeutic effect
    • C) The link between drug storage and efficacy
    • D) The time taken for a drug to be metabolized
    • Answer: B
  15. When switching from one medication to another, healthcare providers often:
    • A) Use the same dosage as the previous medication
    • B) Calculate an equivalent dose based on therapeutic equivalence
    • C) Reduce the dose by half
    • D) Avoid titration altogether
    • Answer: B
  16. The standard practice for determining dosages in drug studies involves:
    • A) Using the lowest effective dose
    • B) Using the maximum tolerated dose
    • C) Using average body weight as the only reference
    • D) Ignoring patient age and health status
    • Answer: A
  17. A physician decides to increase a patient’s medication dosage due to a lack of response. This is an example of:
    • A) Loading dose
    • B) Titration
    • C) Maintenance dose
    • D) Intermittent dosing
    • Answer: B
  18. Drug bioavailability can be influenced by:
    • A) Route of administration
    • B) Formulation type
    • C) Patient health status
    • D) All of the above
    • Answer: D
  19. Which dosing method is preferred for achieving rapid therapeutic levels in acute conditions?
    • A) Continuous infusion
    • B) Bolus dosing
    • C) Intermittent dosing
    • D) Prophylactic dosing
    • Answer: B
  20. What is a common reason for using combination therapy in treatment?
    • A) To reduce costs
    • B) To achieve synergistic effects
    • C) To limit patient education
    • D) To reduce the number of doses
    • Answer: B
  21. The maximum dose of a drug that can be given without causing toxicity is called the:
    • A) Minimum effective dose
    • B) Therapeutic ceiling
    • C) Maximum tolerated dose
    • D) Cumulative dose
    • Answer: C