Master Unit 6 with MCQs on gastrointestinal drugs. Cover key topics like antacids, antiemetics, laxatives, and proton pump inhibitors to boost your exam readiness.
- What is the primary therapeutic use of proton pump inhibitors (PPIs) like omeprazole?
- A) Constipation relief
- B) Diarrhea treatment
- C) Peptic ulcer disease
- D) Antiemetic action
- Answer: C
- Which drug acts by creating a protective barrier over ulcers?
- A) Misoprostol
- B) Sucralfate
- C) Omeprazole
- D) Loperamide
- Answer: B
- Metronidazole is primarily used to treat infections caused by which microorganism?
- A) Fungi
- B) Bacteria
- C) H. pylori
- D) Viruses
- Answer: C
- Which adverse effect is common with prolonged use of aluminum hydroxide antacids?
- A) Diarrhea
- B) Constipation
- C) Headache
- D) Drowsiness
- Answer: B
- What is the main action of antiemetics like metoclopramide?
- A) Inhibits H2 receptors
- B) Blocks D2 receptors
- C) Stimulates gastric acid secretion
- D) Inhibits prostaglandins
- Answer: B
- Which class of drugs does cimetidine belong to?
- A) Proton pump inhibitors
- B) Antacids
- C) H2 receptor antagonists
- D) Laxatives
- Answer: C
- What is the mechanism of action of misoprostol in treating gastric ulcers?
- A) Reduces gastric acid secretion
- B) Neutralizes stomach acidity
- C) Promotes mucus and bicarbonate secretion
- D) Increases peristalsis
- Answer: A
- Loperamide is used to treat which condition?
- A) Nausea
- B) Diarrhea
- C) Constipation
- D) Peptic ulcer
- Answer: B
- Which drug is used as a stool softener?
- A) Sucralfate
- B) Docusate
- C) Metoclopramide
- D) Misoprostol
- Answer: B
- Proton pump inhibitors work by inhibiting which enzyme?
- A) Gastric lipase
- B) Pepsinogen
- C) H+/K+ ATPase
- D) Amylase
- Answer: C
- Which medication is used to treat motion sickness?
- A) Metronidazole
- B) Scopolamine
- C) Omeprazole
- D) Sucralfate
- Answer: B
- What adverse effect is associated with misoprostol?
- A) Constipation
- B) Uterine contractions
- C) Hypertension
- D) Bradycardia
- Answer: B
- Aluminum hydroxide, as an antacid, primarily acts by:
- A) Blocking H2 receptors
- B) Neutralizing gastric acidity
- C) Inhibiting gastric proton pump
- D) Enhancing gastric motility
- Answer: B
- Which agent is commonly used in H. pylori eradication therapy?
- A) Sucralfate
- B) Omeprazole
- C) Metronidazole
- D) Misoprostol
- Answer: C
- Castor oil acts as a:
- A) Osmotic laxative
- B) Stimulant laxative
- C) Stool softener
- D) Antiemetic
- Answer: B
- What is a contraindication for the use of loperamide?
- A) Chronic constipation
- B) Infectious diarrhea
- C) Hypertension
- D) Peptic ulcer disease
- Answer: B
- Which condition can be treated with H2 receptor antagonists?
- A) Asthma
- B) Diabetes
- C) Gastroesophageal reflux disease (GERD)
- D) Hypertension
- Answer: C
- Dimenhydrinate is classified as a/an:
- A) H2 receptor antagonist
- B) Antiemetic
- C) Laxative
- D) Proton pump inhibitor
- Answer: B
- The therapeutic effect of lactulose involves:
- A) Increasing bile production
- B) Acting as an osmotic laxative
- C) Neutralizing stomach acid
- D) Reducing bile flow
- Answer: B
- Which drug is commonly used for peptic ulcer prevention in patients taking NSAIDs?
- A) Metronidazole
- B) Sucralfate
- C) Misoprostol
- D) Loperamide
- Answer: C
- Antacids should not be taken with which class of drugs due to absorption interference?
- A) Antibiotics
- B) Antihistamines
- C) Diuretics
- D) Analgesics
- Answer: A
- What is the mechanism of action of H2 antagonists like cimetidine?
- A) Inhibit proton pumps
- B) Block histamine at H2 receptors
- C) Stimulate mucus secretion
- D) Neutralize gastric acid
- Answer: B
- Scopolamine is most effective in treating:
- A) Peptic ulcers
- B) Motion sickness
- C) Constipation
- D) GERD
- Answer: B
- A common side effect of proton pump inhibitors is:
- A) Hypertension
- B) Constipation
- C) Increased gastric bacteria
- D) Tachycardia
- Answer: C
- Which class of drugs is used to enhance mucosal protection in peptic ulcer disease?
- A) Proton pump inhibitors
- B) H2 antagonists
- C) Mucosal protective agents
- D) Antacids
- Answer: C
- Docusate acts by:
- A) Neutralizing stomach acid
- B) Stimulating peristalsis
- C) Softening stool by emulsifying fecal matter
- D) Blocking D2 receptors
- Answer: C
- Which drug is used to accelerate gastric emptying?
- A) Metoclopramide
- B) Sucralfate
- C) Misoprostol
- D) Loperamide
- Answer: A
- Omeprazole is used primarily to treat:
- A) Constipation
- B) GERD
- C) Asthma
- D) Hypertension
- Answer: B
- Which of the following is an osmotic laxative?
- A) Sucralfate
- B) Lactulose
- C) Metoclopramide
- D) Scopolamine
- Answer: B
- Dimenhydrinate is most commonly used to manage:
- A) GERD
- B) Constipation
- C) Motion sickness
- D) Peptic ulcers
- Answer: C
- Aluminum hydroxide may cause which gastrointestinal side effect?
- A) Diarrhea
- B) Constipation
- C) Nausea
- D) Vomiting
- Answer: B
- The primary action of sucralfate in treating ulcers is to:
- A) Neutralize stomach acid
- B) Create a protective barrier
- C) Reduce gastric motility
- D) Stimulate bile secretion
- Answer: B
- Which drug can prevent NSAID-induced ulcers by increasing mucus production?
- A) Sucralfate
- B) Omeprazole
- C) Misoprostol
- D) Cimetidine
- Answer: C
- Prolonged use of proton pump inhibitors may increase the risk of:
- A) Bacterial overgrowth
- B) Hypertension
- C) Constipation
- D) Acid reflux
- Answer: A
- Which drug class does metoclopramide belong to?
- A) Antacids
- B) Antiarrhythm
ics
– C) Prokinetic agents
– D) Laxatives
– Answer: C
- Scopolamine prevents motion sickness by blocking:
- A) H2 receptors
- B) Acetylcholine at muscarinic receptors
- C) Dopamine receptors
- D) Gastric proton pumps
- Answer: B
- A laxative that works by increasing water content in stools is:
- A) Sucralfate
- B) Misoprostol
- C) Lactulose
- D) Metoclopramide
- Answer: C
- Which medication is used to reduce nausea in chemotherapy patients?
- A) Scopolamine
- B) Metoclopramide
- C) Loperamide
- D) Sucralfate
- Answer: B
- Proton pump inhibitors are indicated for the treatment of:
- A) Asthma
- B) GERD and ulcers
- C) Hypertension
- D) Constipation
- Answer: B
- Which gastrointestinal drug can increase uterine contractions?
- A) Omeprazole
- B) Sucralfate
- C) Misoprostol
- D) Loperamide
- Answer: C
- Docusate is best used as a:
- A) Stool softener
- B) Proton pump inhibitor
- C) Antiemetic
- D) Antidiarrheal
- Answer: A
- Aluminum hydroxide’s primary mechanism is:
- A) Gastric emptying enhancement
- B) Neutralizing stomach acid
- C) Promoting peristalsis
- D) Stimulating bile secretion
- Answer: B
- Which adverse effect is associated with scopolamine?
- A) Diarrhea
- B) Dry mouth
- C) Increased appetite
- D) Hypotension
- Answer: B
- Lactulose helps in constipation by:
- A) Blocking sodium channels
- B) Reducing bile secretion
- C) Increasing osmotic pressure in the colon
- D) Neutralizing stomach acid
- Answer: C
- Which drug works by inhibiting H+/K+ ATPase?
- A) Misoprostol
- B) Omeprazole
- C) Sucralfate
- D) Metoclopramide
- Answer: B
- Scopolamine is used primarily for:
- A) Diarrhea
- B) Motion sickness
- C) Heartburn
- D) Constipation
- Answer: B
- Proton pump inhibitors should be taken:
- A) After meals
- B) Before meals
- C) At bedtime
- D) Only with antacids
- Answer: B
- Which condition is commonly treated with misoprostol?
- A) GERD
- B) Constipation
- C) NSAID-induced ulcers
- D) Motion sickness
- Answer: C
- Dimenhydrinate is an example of a/an:
- A) H2 receptor blocker
- B) Laxative
- C) Antiemetic
- D) Antacid
- Answer: C
- The primary action of loperamide in the gastrointestinal tract is:
- A) Stimulating peristalsis
- B) Inhibiting gastric secretion
- C) Reducing bowel motility
- D) Neutralizing stomach acid
- Answer: C