Prepare with MCQs on Autacoids and Their Antagonists. Cover key concepts like histamine, serotonin, prostaglandins, and their inhibitors for effective exam preparation.
- What are autacoids?
- A) Systemic hormones
- B) Locally acting hormones
- C) Neurotransmitters
- D) Enzymes
- Answer: B
- Which of the following is an example of an autacoid?
- A) Insulin
- B) Histamine
- C) Glucagon
- D) Dopamine
- Answer: B
- Histamine primarily binds to which receptors?
- A) H1 and H2
- B) Alpha and beta
- C) Muscarinic
- D) Dopaminergic
- Answer: A
- Which receptor is responsible for histamine-induced gastric acid secretion?
- A) H1
- B) H2
- C) H3
- D) H4
- Answer: B
- H1 receptor antagonists are primarily used to treat:
- A) Heartburn
- B) Allergies
- C) Diabetes
- D) Hypertension
- Answer: B
- Which of the following is a therapeutic use of prostaglandins?
- A) Hypertension treatment
- B) Abortion induction
- C) Diabetes management
- D) Muscle relaxation
- Answer: B
- Histamine is involved in which of the following responses?
- A) Anti-inflammatory
- B) Allergic and inflammatory reactions
- C) Neuroprotection
- D) Protein synthesis
- Answer: B
- What is the primary action of H2 antagonists?
- A) Stimulate gastric acid production
- B) Block gastric acid secretion
- C) Increase allergic reactions
- D) Stimulate bronchoconstriction
- Answer: B
- Misoprostol is a synthetic analogue of:
- A) Histamine
- B) Prostaglandin E1
- C) Serotonin
- D) Bradykinin
- Answer: B
- Which condition is treated using H2 receptor antagonists?
- A) Allergic rhinitis
- B) Peptic ulcer
- C) Asthma
- D) Hypertension
- Answer: B
- Serotonin acts as a:
- A) Neurotransmitter and local hormone
- B) Protein synthesis enzyme
- C) Bone growth stimulant
- D) Vitamin precursor
- Answer: A
- A common use of H1 antihistamines is for:
- A) Ulcer treatment
- B) Insomnia
- C) Epilepsy
- D) Muscle cramps
- Answer: B
- Which autacoid is known to mediate platelet aggregation?
- A) Histamine
- B) Serotonin
- C) Prostaglandin
- D) Bradykinin
- Answer: B
- Histamine H1 receptor antagonists can also be used as:
- A) Antidiabetic agents
- B) Antiemetics
- C) Antiviral drugs
- D) Antibacterial agents
- Answer: B
- Which receptor does misoprostol bind to?
- A) Dopamine receptors
- B) Prostaglandin receptors
- C) Beta-adrenergic receptors
- D) Acetylcholine receptors
- Answer: B
- Prostaglandins are derived from which type of fatty acids?
- A) Saturated fatty acids
- B) Unsaturated fatty acids
- C) Amino acids
- D) Steroids
- Answer: B
- What is the main therapeutic use of H2 antihistamines?
- A) Sedation
- B) Acid suppression
- C) Anti-inflammatory action
- D) Muscle relaxation
- Answer: B
- Which autacoid is released during an allergic reaction?
- A) Dopamine
- B) Acetylcholine
- C) Histamine
- D) Serotonin
- Answer: C
- The main effect of serotonin in the gastrointestinal system is:
- A) Reducing acid secretion
- B) Stimulating smooth muscle contraction
- C) Inhibiting digestion
- D) Inducing vomiting
- Answer: B
- Which of the following is a side effect of first-generation antihistamines?
- A) Hypertension
- B) Sedation
- C) Hyperglycemia
- D) Tachycardia
- Answer: B
- H2 receptor antagonists are used to treat:
- A) Bronchospasm
- B) Peptic ulcers
- C) Allergies
- D) Depression
- Answer: B
- Which autacoid plays a role in migraine pathophysiology?
- A) Histamine
- B) Prostaglandin
- C) Serotonin
- D) Dopamine
- Answer: C
- Prostaglandins can be used in the management of:
- A) Hypertension
- B) Heart failure
- C) Glaucoma
- D) Diabetes
- Answer: C
- Misoprostol is contraindicated in:
- A) Pregnancy
- B) Peptic ulcer disease
- C) Asthma
- D) Glaucoma
- Answer: A
- Which of the following receptors does serotonin primarily bind to?
- A) Alpha receptors
- B) H1 receptors
- C) 5-HT receptors
- D) Beta receptors
- Answer: C
- H1 antihistamines are effective in treating:
- A) Acid reflux
- B) Allergic rhinitis
- C) Hypertension
- D) Constipation
- Answer: B
- Histamine can cause which of the following effects in the lungs?
- A) Bronchodilation
- B) Bronchoconstriction
- C) Increased surfactant production
- D) Reduced respiratory rate
- Answer: B
- The primary action of H1 antihistamines in motion sickness is:
- A) Enhancing GABA activity
- B) Blocking acetylcholine receptors
- C) Inhibiting histamine H1 receptors
- D) Activating serotonin receptors
- Answer: C
- Prostaglandins are involved in the regulation of:
- A) Blood glucose levels
- B) Renal blood flow
- C) Neuronal firing
- D) Protein synthesis
- Answer: B
- Antihistamines used for insomnia typically belong to which generation?
- A) First-generation
- B) Second-generation
- C) Third-generation
- D) Non-sedating
- Answer: A
